This is an archive of information released in the past.
Disclaimer: It may contain broken links or outdated information. Some parts may not function in current web browsers.
*Visit https://humans-in-space.jaxa.jp/en/ for the latest information.
Japan Aerospace Exploration Agency
RIKEN
Kagawa Nutrition University
Waseda University
Japan Aerospace Exploration Agency (JAXA) developed mouse habitat cage units (HCUs) equipped with an artificial gravity-producing centrifuge, called the Multiple Artificial-gravity Research System (MARS), and conducted the first one-month mission under μg and artificial 1g in the ISS Kibo module in 2016 (the first JAXA mouse mission). The experimental platform MARS enabled to evaluate impacts of μg and artificial gravity on mice, because environmental conditions in μg and artificial 1g sections were identical except gravity (Shiba, D et al. Scientific Reports 2017).
The MARS underwent improvement in water leakage that happened in a μg section during the first JAXA mouse mission, and the improved MARS was used in the second JAXA mouse mission in the ISS Kibo module. Twelve mice were divided into four groups of three, with each group fed a diet either with or without prebiotics, fructo-oligosaccharide (FOS) and housed singly either at μg or artificial 1g for 30 days. Changes in mouse body weight were evaluated to examine the impact of FOS and gravity. The modified MARS showed no water leakage during the second mission. Achievement of environmentally stable MARS should open new space research possibilities. The improved MARS will be useful in evaluating artificial gravity and dietary intervention for space flown mice. These results were published in Nature partner online journal, npj Microgravity on July 8, 2019.
Manuscripts on the effects of FOS are in preparation by researchers at RIKEN, Kagawa Nutrition University and Waseda University.
Copyright 2007 Japan Aerospace Exploration Agency | Site Policy |