This is an archive of information released in the past. Disclaimer: It may contain broken links or outdated information. Some parts may not function in current web browsers.
 
ISS TopJAXA Top  sitemap
 

Subject 6:
Alterations of oncogenes and tumor suppressor genes caused by space radiation and microgravity in cultured human cells
Return to
previous page

Principal Investigator :
Mitsuo Ikenaga, Ph.D.
(Kyoto University)

Objective : The basic data to estimate possible effects of cosmic radiation on astronauts will be obtained.

Experiment outline : In space environment, exposure to cosmic radiation is unavoidable. Human cells are inoculated to cell culture modules (CCMs) and loaded on the Space Shuttle. After recovery of cells on Earth, the effects of cosmic radiation and the zero-gravity on the genes are analyzed.

Expected outcome : If the frequencies of mutations and of other radiation effects in the flight samples are essentially the same as those in the control samples kept on Earth, we can conclude that cosmic radiation and the zero-gravity during a short-term space flight do not cause significant effects on human genes. In contrast, if the cells returned from space exhibit a higher rate of mutation compared with ground control, then the effects of long-term space flight should be investigated in more detail using the coming International Space Station.

Experimental unit : Cell Culture Module (CCM)



Return to
previous page
JAXA Top Site Policy